Zegalogue dosage: Form, strength, how to use, and more

Zegalogue (dasiglucagon) is a prescription drug that’s used to treat severely low blood sugar levels. The drug comes as a liquid solution for injecting under the skin as needed.

Zegalogue is used to treat severely low blood sugar levels in adults and certain children with diabetes.

The active ingredient in Zegalogue is dasiglucagon. (An active ingredient is what makes a drug work.) Zegalogue belongs to a group of drugs called glucagon analogs.

This article describes the dosage of Zegalogue, as well as its strength and how to give it. To learn more about Zegalogue, see this in-depth article.

What is Zegalogue’s dosage?

This section describes the usual dosages of Zegalogue. Keep reading to learn more.

What is Zegalogue’s form?

Zegalogue is available as a liquid solution that you inject under your skin. It comes in an auto-injector and in a prefilled syringe for a single dose.

What strength does Zegalogue come in?

Zegalogue comes in one strength of 0.6 milligrams per 0.6 milliliter (mg/mL).

What is the usual dosage of Zegalogue in adults?

The information below describes the dosage that’s commonly used or recommended. But be sure to use the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for severe hypoglycemia

Zegalogue is used to manage severely low blood sugar levels in adults with diabetes.

Your doctor will explain how to monitor for signs of a very low blood sugar level. They’ll also show you or a caregiver how to give a dose of Zegalogue.

The typical dosage is 0.6 mg as a onetime dose. If your blood sugar level hasn’t improved 15 minutes after a dose of Zegalogue, you may use a second dose.

After giving a dose of Zegalogue, immediately call 911 or your local emergency medical service. You may need other treatments to raise your blood sugar to a safe level. Or you may need them to maintain a safe level to avoid complications from severely low blood sugar levels.

If you have questions about your dosage of Zegalogue, talk with your doctor to learn more.

What’s the dosage of Zegalogue children?

Zegalogue is used to manage severely low blood sugar levels in children ages 6 years and older who have diabetes.

The dosage used in children is the same as the dosage used in adults. To learn more, see the β€œWhat is the usual dosage of Zegalogue in adults?” section above.

For more information about Zegalogue’s dosage for children, talk with your child’s doctor or a pharmacist.

Is Zegalogue used long term?

Yes, it is. But it’s only for emergency treatment of severely low blood sugar levels in people and certain children with diabetes. It’s not used daily or regularly. Your doctor will discuss signs of a very low blood sugar level. They’ll also discuss when to administer a dose of Zegalogue.

If you have questions about long-term use of Zegalogue, talk with your doctor.

What factors can affect my dosage?

Doctors usually prescribe the same recommended dosage for people using Zegalogue. But sometimes you may need more than one dose to treat severely low blood sugar levels. This may depend on:

  • the severity of low blood sugar
  • how your body responds to Zegalogue

How is Zegalogue given?

You or your caregiver will inject Zegalogue under the skin of your thigh, outer upper arm, buttocks, or lower abdomen. Zegalogue is only for emergency treatment of severely low blood sugar levels.

If your blood sugar level hasn’t improved 15 minutes after one dose of Zegalogue, you may use a second dose of Zegalogue.

Your doctor or another healthcare professional will explain how to recognize signs of severely low blood sugar levels. They’ll also show you or a caregiver how to give a dose of Zegalogue.

Your doctor may prescribe the auto-injector or the prefilled syringe. Follow the directions from your doctor or pharmacist for giving a dose of Zegalogue. This video also explains how to give a dose of Zegalogue.

After a dose

After giving a dose of Zegalogue, call 911 or your local emergency medical service immediately.

Once you’re able to eat or drink, you’ll need to eat sources of sugar that are fast-acting and long-acting. Examples are:

  • fast-acting: fruit juice
  • long-acting: crackers with cheese or peanut butter

Be sure to let your doctor know once you use Zegalogue. They can discuss your condition. If needed, they can determine whether anything needs to be adjusted. This may include your diabetes medications, your diet, and your lifestyle.

For information on the expiration, storage, and disposal of Zegalogue, talk with your doctor or pharmacist.

Accessible drug containers and labels

Some pharmacies provide medication labels that:

  • have large print
  • use braille
  • feature a code you can scan with a smartphone to change the text to audio

Check whether your pharmacy offers these accessibility features. If it doesn’t, your doctor or pharmacist may be able to recommend pharmacies that do.

What should be done in case of overdose?

Do not use more Zegalogue than your doctor prescribes, as this can lead to harmful effects.

What to do in case you use too much Zegalogue

Call your doctor right away if you think you’ve used too much Zegalogue. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Frequently asked questions

Below are answers to some commonly asked questions about Zegalogue’s dosage.

Is Zegalogue’s dosage similar to the dosages of Gvoke or Baqsimi?

No, it’s not. Zegalogue (dasiglucagon), Gvoke (glucagon), and Baqsimi (glucagon) all treat very low blood sugar levels. But their active ingredients, dosage forms, and dose in milligrams have some differences.

Zegalogue and Gvoke come as solutions for injection under your skin. You typically give both as a one-time dose for severely low blood sugar levels in the lower abdomen, thigh, or outer upper arm. You can also inject Zegalogue into the buttocks.

Baqsimi comes as a nasal powder that you spray into one nostril for severely low blood sugar levels. You typically give it as a one-time dose.

Your doctor will prescribe the drug and the dosage that’s right for you. To learn more about how these drugs compare, talk with your doctor.

How long does it take for Zegalogue to start working?

Zegalogue starts to work immediately after you give a dose. You should start to feel better shortly after a dose. Even so, you or a caregiver should call 911 or your local emergency medical service right after giving a dose of Zegalogue.

If your blood sugar level doesn’t improve 15 minutes after a dose of Zegalogue, you or a caregiver may give a second dose.

If you have other questions about what to expect from your Zegalogue treatment, talk with your doctor.

What should I ask my doctor?

The sections above describe the usual dosage provided by Zegalogue’s drugmaker. If your doctor recommends this drug, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Zegalogue without your doctor’s recommendation. Only use Zegalogue exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • Does giving two doses of Zegalogue mean I need to adjust my diabetes medications?
  • Will I experience more side effects if I need to have two doses of Zegalogue?
  • How does Zegalogue’s dosage compare with over-the-counter medications that treat low blood sugar levels?

To learn more about Zegalogue, see this β€œZegalogue (dasiglucagon)” article.

4 Comments

  1. Sure thing! Here’s my comment:

    This is a comprehensive and well-explained breakdown of Zegalogue dosage! It’s really helpful to have all this detailed information about the form, strength, and proper usage in one place. Thanks for making it easier to understand how to use this medication safely and effectively. 🌟

  2. I found this article on Zegalogue dosage very informative! It clearly explains the different forms and strengths available, and the detailed instructions on how to use it are really helpful. Great resource for anyone needing to understand this medication better. Thanks for sharing!

  3. This post is incredibly informative! Understanding the correct dosage, form, strength, and usage instructions for Zegalogue is crucial for safe and effective treatment. The detailed breakdown provided here can really help patients and caregivers feel more confident and ensure they are using it correctly. Thanks for sharing such valuable information!

  4. This is a very informative post! I’ve been curious about the specific details regarding Zegalogue, especially in terms of proper dosage and administration. The breakdown of the form and strength, along with how to use it, is really helpful for anyone needing to manage severe hypoglycemia. Thanks for making it easier to understand!

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