Kisunla and Interactions: Other Drugs, Supplements, and More
Kisunla (donanemab-azbt) is a prescription drug that’s used to treat Alzheimer’s disease in adults. This drug currently isn’t known to interact with other drugs.
Note: As a person’s condition progresses, they may need help reading or understanding certain information about their treatment plan. This article contains details that may help caregivers learn more about key aspects of Kisunla.
Does Kisunla interact with other drugs?
An interaction can occur because one substance causes another substance to have a different effect than expected. Interactions can also occur if you have certain health conditions.
Currently, Kisunla isn’t known to interact with other drugs. But this doesn’t mean interactions won’t be discovered in the future. For example, new drugs may be developed that interact with Kisunla.
Before starting Kisunla treatment, tell your doctor and pharmacist about any prescription medications you take (such as antithrombotic drugs), as well as over-the-counter or other drugs you use.
Sharing this information with them may help prevent possible interactions that may be discovered later. (To learn whether Kisunla interacts with herbs or vitamins and supplements, see the “Are there other interactions with Kisunla?” section.)
If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.
When should I avoid Kisunla?
Certain health conditions or other factors could raise your risk of harm if you use Kisunla. In such cases, your doctor may not prescribe Kisunla for you. These are known as contraindications. Kisunla has one contraindication, which is described below.
If you’ve had an allergic reaction: If you’ve had an allergic reaction to Kisunla or any of its ingredients, your doctor likely won’t prescribe Kisunla for you. This is because using the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better options for you.
Does Kisunla interact with alcohol?
Kisunla is not known to interact with alcohol. But alcohol can worsen Alzheimer’s disease. Because of this, your doctor may recommend that you limit the amount of alcohol you drink.
If you have questions about consuming alcohol while using Kisunla, talk with your doctor or pharmacist.
Are there other interactions with Kisunla?
Kisunla may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests. See below for details. Note that this information does not include all other possible interactions with Kisunla.
Does Kisunla interact with supplements?
Before you start Kisunla treatment, talk with your doctor and pharmacist about any herbs or vitamins and supplements you take. Sharing this information with them may help you avoid possible interactions.
If you have questions about interactions that may affect you, talk with your doctor or pharmacist.
Kisunla and herbs
There are currently no reports of Kisunla interacting with herbs. But this doesn’t mean that interactions with herbs won’t be recognized in the future.
For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products while using Kisunla.
Kisunla and vitamins
There are currently no reports of Kisunla interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future.
For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products while using Kisunla.
Does Kisunla interact with food?
There are currently no reports of Kisunla interacting with food. If you have questions about eating certain foods during your treatment with Kisunla, talk with your doctor.
Does Kisunla interact with vaccines or lab tests?
There are currently no reports of Kisunla interacting with vaccines or lab tests. If you have questions about receiving certain vaccines or having lab tests done during your Kisunla treatment, talk with your doctor.
Does Kisunla interact with cannabis or CBD?
There are currently no reports of Kisunla interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But, as with any drug or supplement, talk with your doctor before using cannabis with Kisunla.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Does my health history affect whether I should take Kisunla?
Certain medical conditions or other health factors may raise the risk of interactions with Kisunla. Before using Kisunla, talk with your doctor about your health history. They’ll determine whether Kisunla is right for you.
Health conditions or other factors that might interact with Kisunla include:
A certain genetic risk factor: Having a genetic risk factor (homozygous apolipoprotein E ε4 gene carrier) can increase your risk of amyloid-related imaging abnormalities (ARIA). Kisunla has a boxed warning about the risk of ARIA. To learn more, see the “Boxed warning” section.
Obstruction (blockage) in your intestines: Kisunla can cause an intestinal obstruction. If you have an existing obstruction, Kisunla may worsen it.
Pregnancy: It’s not known whether Kisunla is safe to use during pregnancy. If you’re pregnant or planning a pregnancy, talk with your doctor before starting Kisunla treatment.
Breastfeeding: It’s not known whether it’s safe to use Kisunla while breastfeeding. It’s not known whether the drug passes into breast milk and, if so, what side effects (if any) this may cause in a child who’s breastfed. If you’re breastfeeding or planning to do so, talk with your doctor about your options.
Allergic reaction: If you’ve had an allergic reaction to Kisunla or any of its ingredients, your doctor will likely not prescribe Kisunla. This is because using the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better choices for you.
How can I prevent interactions?
Taking certain steps can help you avoid interactions with Kisunla. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:
It’s also important to understand Kisunla’s label and other paperwork that may come with the drug. Colored stickers that describe interactions may be on the label. And the paperwork (sometimes called the patient package insert or medication guide) may have other details about interactions. (If you did not get paperwork with Kisunla, ask your pharmacist to print a copy for you.)
If you have trouble reading or understanding this information, your doctor or pharmacist can help.
Using Kisunla exactly as prescribed can also help prevent interactions.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
