Oriahnn dosage: Form, strengths, how to use, and more
Oriahnn (elagolix, estradiol, and norethindrone acetate) is prescribed to treat heavy periods from uterine fibroids. The drug comes as capsules. You swallow a specific one in the morning and a different one in the evening.
Oriahnn is used in adults to treat heavy periods from uterine fibroids. It’s approved only for females who have not experienced menopause. (In this article, we use the term “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.)
Oriahnn contains three active ingredients. (An active ingredient is what makes a drug work.) These ingredients and the groups of drugs they belong to are:
This article describes the dosage of Oriahnn, as well as its strengths and how to take it. To learn more about Oriahnn, see this in-depth article.
Boxed warning: Risk of blood clots and certain blood vessel problems
Oriahnn has a boxed warning about the risk of blood clots and certain blood vessel problems. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.
Oriahnn contains the hormones estradiol (a form of estrogen) and progestin (synthetic version of progesterone). Taking medication containing these hormones may increase your risk of blood clots in your lungs or certain veins. Symptoms of a blood clot may include shortness of breath or swelling or warmth in a certain area.
Taking estradiol and progestin also may increase your risk of other blood vessel problems. These include stroke and heart attack. Symptoms of stroke may include slurring your words or becoming weak on one side of your body. Symptoms of heart attack may include chest pain or lightheadedness.
Due to these risks, doctors will not prescribe Oriahnn if you have or ever had a blood clot or blood vessel problem.
It’s also likely that doctors won’t prescribe Oriahnn if you’re over age 35 years and smoke. Also, they likely won’t prescribe Oriahnn if you have high blood pressure that’s not well managed. This is because females in both of these groups are at higher risk of these problems. (In this article, we use the term “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.)
You also may be at higher risk of blood clots or other blood vessel problems if you have:
Your doctor will watch for signs of a blood clot or other problems with your blood vessels. If you develop any, they likely will have you stop taking Oriahnn. Let your doctor know if you notice sudden changes in your vision, including seeing double. If you do, your doctor may have you stop taking Oriahnn.
For some surgeries, your doctor may have you stop taking Oriahnn 4–6 weeks before if possible. These include surgeries that raise your risk of blood clots afterward. They also include surgeries that may require you to move less than you’re used to during your recovery.
What is Oriahnn’s dosage?
The table below highlights the basics of Oriahnn’s dosage. All doses are listed in milligrams (mg).
| When | Dose | Capsule |
|---|---|---|
| morning | 1 capsule | white and yellow, imprinted with “EL300 AM” |
| evening | 1 capsule | white and light blue, imprinted with “EL300 PM” |
Keep reading for more details about Oriahnn’s dosage.
What is Oriahnn’s form?
Oriahnn is available as oral capsules. A specific capsule is for morning doses, and a specific capsule is for evening doses.
Blister packaging separates morning and evening capsules.
What strengths does Oriahnn come in?
Oriahnn comes in two strengths that are prescribed together. This is because capsules for the morning dose differ from capsules for the evening dose. The strengths of each capsule and its active ingredients are:
What is the usual dosage of Oriahnn?
The information below describes the dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.
Dosage for heavy menstrual bleeding due to uterine fibroids
Oriahnn is used in adults to treat heavy periods from uterine fibroids. It’s approved only for females who have not experienced menopause. (In this article, we use the term “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.)
The typical Oriahnn dosage is:
Do not swap the morning and evening capsules. This is because each contains different ingredients.
Is Oriahnn taken long term?
No, Oriahnn isn’t usually taken as a long-term treatment. Studies recommend that you don’t take Oriahnn for more than 24 months (2 years). This recommendation is to help limit your risk of bone loss.
What factors can affect my dosage?
The dosage of Oriahnn you’re prescribed may depend on several factors. These include:
How is Oriahnn taken?
In the morning, you swallow one white and yellow capsule (imprinted with “EL300 AM”). In the evening, you swallow one white and light blue capsule (imprinted with “EL300 PM”). You may take your doses with or without food. But take each dose at about the same time daily.
Do not swap the morning and evening capsules. This is because each contains different ingredients. (Blister packaging separates your morning and evening doses.)
If you have difficulty swallowing capsules, see this article for tips on how to take this form of medication.
For information on the expiration, storage, and disposal of Oriahnn, talk with your doctor or pharmacist.
Accessible drug containers and labels
Some pharmacies provide medication labels that:
Check whether your current pharmacy offers these accessibility features. If it doesn’t, your doctor or pharmacist may be able to recommend pharmacies that do.
Let your pharmacist know if you have difficulty accessing pills in blister packaging. (This may require having to push a pill through some type of paper. Or it may require having to peel away a paper to access the pill.) They may have tips to help. Or they may be able to supply Oriahnn in another container that’s easier to open.
What if I miss a dose?
If you missed a morning or evening dose, check when it was due. If it was due within the past 4 hours, take the missed dose. Then, take your next dose at its usual time.
If the missed dose was due more than 4 hours ago, skip the missed dose. Then take your next dose at its usual time.
Don’t double up to make up for a missed dose. Doing so could increase your risk of side effects.
Talk with your doctor or pharmacist if you’re not sure whether you should take a missed dose.
To help you remember to take your dose of Oriahnn on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.
What should be done in case of overdose?
Do not take more Oriahnn than your doctor prescribes, as this can lead to harmful effects.
Symptoms of overdose
Symptoms caused by an overdose can include:
What to do in case you take too much Oriahnn
Call your doctor right away if you think you’ve taken too much Oriahnn. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number). Or go to the nearest emergency room.
Frequently asked questions
Below are answers to some commonly asked questions about Oriahnn’s dosage.
How long does it take for Oriahnn to start working?
Oriahnn starts to work after your first dose. However, studies have shown it may take 1–2 months before you notice reduced symptoms. Your doctor will monitor you during treatment to check whether the drug is working for your condition.
If you have other questions about what to expect from your Oriahnn treatment, talk with your doctor.
Can Oriahnn be taken to stop periods? If so, what’s the dosage?
No, Oriahnn is not taken to stop periods. But Oriahnn is taken to treat heavy periods from uterine fibroids. Because of this, you may find your periods become lighter or shorter.
Because Oriahnn isn’t taken to stop periods, the drugmaker doesn’t provide recommended dosages for this use.
Some oral birth control drugs can extend the time between your periods. (Oriahnn is not birth control.) These provide hormone therapy for a certain number of days (when you don’t have a period). They also provide placebo pills (no active drug) for a certain number of days (when you do have a period). These drugs mean your periods could be weeks or even months apart.
Other birth control drug forms might extend time between periods. These include forms such as an injection, a skin patch, or a device implanted in your arm.
To learn more about treatment options for extending time between periods, talk with your doctor.
What should I ask my doctor?
The sections above describe the usual dosages provided by Oriahnn’s drugmaker. If your doctor recommends this drug, they’ll prescribe the dosage that’s right for you.
Remember, you should not change your dosage of Oriahnn without your doctor’s recommendation. Only take Oriahnn exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.
Here are some examples of questions you may want to ask your doctor:
To learn more about Oriahnn, see this “All About Oriahnn” article.
This is super helpful information! I’ve been looking for a comprehensive guide on Oriahnn dosage and this post breaks down everything I needed to know. Thanks for sharing the different forms, strengths, and tips on how to use it effectively. Keep up the great work!
This is a wonderfully comprehensive guide on Oriahnn dosage. The breakdown of forms, strengths, and proper usage is incredibly helpful for anyone prescribed this medication. It’s reassuring to have such detailed information all in one place! Thank you for putting this together.
This article provides a thorough and informative overview of Oriahnn, covering everything from dosage forms and strengths to detailed instructions on usage. It’s a great resource for anyone prescribed this medication. Thanks for making complex medical information accessible!
This article provides an in-depth look into Oriahnn, covering its various forms and strengths. The clear instructions on how to properly use the medication are incredibly helpful. Thanks for shedding light on this treatment option!
Thanks for the detailed information on Oriahnn dosage! It’s really helpful to know the different forms and strengths available. Can you also provide some insights on potential side effects and precautions to keep in mind while using this medication? That would be super helpful!