Tenofovir
**Tenofovir: An Antiviral Medication for HIV and Hepatitis B**
Tenofovir, a nucleoside reverse transcriptase inhibitor (NRTI), is a potent antiviral medication used to treat HIV-1 and hepatitis B virus (HBV) infections. It works by interfering with the viral replication process, preventing the virus from multiplying and causing harm to the body.
**Key Benefits:**
* Suppresses HIV-1 and HBV viral load
* Reduces the risk of HIV transmission
* Improves liver function in chronic HBV patients
* Well-tolerated with minimal side effects
**Indications:**
* HIV-1 infection, including treatment-naive and experienced patients
* Chronic hepatitis B infection in adults and adolescents
**Dosing:**
* HIV-1: 300 mg once daily
* Hepatitis B: 300 mg once daily or 245 mg with pegylated interferon
**Side Effects:**
* Nausea and vomiting
* Headache
* Fatigue
* Diarrhea
* Flatulence
**Contraindications:**
* Hypersensitivity to tenofovir
* Patients with severe renal impairment
**Interactions:**
* Interactions with other antiretroviral medications (e.g., Atazanavir)
* Concomitant use with nephrotoxic drugs can increase renal toxicity
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